| Houston to University Place (Washington) | 1,882.08 mi (3,028.92 km) |
| Houston to Upland (California) | 1,336.63 mi (2,151.10 km) |
| Houston to Upper Arlington (Ohio) | 991.99 mi (1,596.46 km) |
| Houston to Upper Grand Lagoon (Florida) | 577.86 mi (929.97 km) |
| Houston to Upper Montclair (New Jersey) | 1,412.11 mi (2,272.56 km) |
| Houston to Urbana (Illinois) | 820.72 mi (1,320.82 km) |
| Houston to Urbana (Maryland) | 1,216.70 mi (1,958.08 km) |
| Houston to Urbana (Ohio) | 969.25 mi (1,559.86 km) |
| Houston to Urbandale (Iowa) | 823.87 mi (1,325.89 km) |
| Houston to Utica (New York) | 1,442.97 mi (2,322.23 km) |
| Houston to Uvalde (Texas) | 266.89 mi (429.52 km) |
| Houston to Vacaville (California) | 1,625.21 mi (2,615.52 km) |
| Houston to Vadnais Heights (Minnesota) | 1,062.61 mi (1,710.11 km) |
| Houston to Vail (Arizona) | 919.59 mi (1,479.93 km) |
| Houston to Valdosta (Georgia) | 725.64 mi (1,167.80 km) |
