| Washington (District of Columbia) to Fort Pierce | 815.97 mi (1,313.17 km) |
| Baltimore (Maryland) to Fort Pierce | 848.31 mi (1,365.22 km) |
| Philadelphia (Pennsylvania) to Fort Pierce | 918.98 mi (1,478.96 km) |
| Houston (Texas) to Fort Pierce | 926.39 mi (1,490.88 km) |
| St. Louis (Missouri) to Fort Pierce | 962.46 mi (1,548.92 km) |
| Brooklyn (New York) to Fort Pierce | 983.59 mi (1,582.94 km) |
| New York (New York) to Fort Pierce | 986.91 mi (1,588.27 km) |
| Queens (New York) to Fort Pierce | 993.11 mi (1,598.26 km) |
| Detroit (Michigan) to Fort Pierce | 1,045.09 mi (1,681.90 km) |
| Dallas (Texas) to Fort Pierce | 1,047.90 mi (1,686.44 km) |
| Chicago (Illinois) to Fort Pierce | 1,078.68 mi (1,735.96 km) |
| Boston (Massachusetts) to Fort Pierce | 1,153.38 mi (1,856.19 km) |
| Miami (Florida) to Fort Pierce | 113.71 mi (183.00 km) |
| Minneapolis (Minnesota) to Fort Pierce | 1,405.82 mi (2,262.45 km) |
| Denver (Colorado) to Fort Pierce | 1,640.95 mi (2,640.85 km) |
| Tampa (Florida) to Fort Pierce | 134.43 mi (216.34 km) |
| Phoenix (Arizona) to Fort Pierce | 1,929.05 mi (3,104.51 km) |
| Las Vegas (Nevada) to Fort Pierce | 2,125.57 mi (3,420.77 km) |
| San Diego (California) to Fort Pierce | 2,218.10 mi (3,569.69 km) |
| Riverside (California) to Fort Pierce | 2,234.68 mi (3,596.37 km) |
| Los Angeles (California) to Fort Pierce | 2,292.88 mi (3,690.03 km) |
| San Francisco (California) to Fort Pierce | 2,529.58 mi (4,070.97 km) |
| Portland (Oregon) to Fort Pierce | 2,622.24 mi (4,220.09 km) |
| Seattle (Washington) to Fort Pierce | 2,644.97 mi (4,256.67 km) |
| Atlanta (Georgia) to Fort Pierce | 500.45 mi (805.39 km) |
