| Humenne to Ruzomberok | 118.17 mi (190.18 km) |
| Humenne to Sabinov | 39.02 mi (62.80 km) |
| Humenne to Sal'a | 192.11 mi (309.17 km) |
| Humenne to Samorin | 219.58 mi (353.38 km) |
| Humenne to Senec | 211.86 mi (340.96 km) |
| Humenne to Senica | 207.31 mi (333.63 km) |
| Humenne to Sered' | 195.88 mi (315.23 km) |
| Humenne to Skalica | 212.68 mi (342.27 km) |
| Humenne to Smizany | 62.52 mi (100.62 km) |
| Humenne to Snina | 11.90 mi (19.16 km) |
| Humenne to Spisska Nova Ves | 60.78 mi (97.82 km) |
| Humenne to Stara L'ubovna | 61.22 mi (98.53 km) |
| Humenne to Stara Tura | 191.70 mi (308.52 km) |
| Humenne to Stropkov | 21.90 mi (35.24 km) |
| Humenne to Stupava | 227.32 mi (365.83 km) |
