| Ioannina to Santeramo in Colle | 229.33 mi (369.08 km) |
| Ioannina to Santo Stefano di Magra | 641.77 mi (1,032.83 km) |
| Ioannina to Santo Stino di Livenza | 589.27 mi (948.33 km) |
| Ioannina to Sarezzo | 680.24 mi (1,094.73 km) |
| Ioannina to Sarno | 338.30 mi (544.44 km) |
| Ioannina to Saronno | 727.00 mi (1,169.99 km) |
| Ioannina to Sarzana | 638.32 mi (1,027.28 km) |
| Ioannina to Sassari | 652.39 mi (1,049.91 km) |
| Ioannina to Sasso Marconi | 590.94 mi (951.02 km) |
| Ioannina to Sassuolo | 616.01 mi (991.37 km) |
| Ioannina to Sava | 181.10 mi (291.46 km) |
| Ioannina to Saviano | 344.85 mi (554.99 km) |
| Ioannina to Savigliano | 758.42 mi (1,220.56 km) |
| Ioannina to Savignano sul Panaro | 603.07 mi (970.55 km) |
| Ioannina to Savignano sul Rubicone | 531.38 mi (855.17 km) |
