| Ioannina to Setubal | 1,589.68 mi (2,558.35 km) |
| Ioannina to Sever do Vouga | 1,536.66 mi (2,473.01 km) |
| Ioannina to Silves | 1,587.62 mi (2,555.03 km) |
| Ioannina to Sines | 1,596.99 mi (2,570.11 km) |
| Ioannina to Sintra | 1,611.89 mi (2,594.08 km) |
| Ioannina to Sobrado de Paiva | 1,529.13 mi (2,460.90 km) |
| Ioannina to Sobral de Monte Agraco | 1,596.43 mi (2,569.20 km) |
| Ioannina to Soure | 1,556.92 mi (2,505.62 km) |
| Ioannina to Tabua | 1,522.33 mi (2,449.96 km) |
| Ioannina to Tavira | 1,546.99 mi (2,489.65 km) |
| Ioannina to Tomar | 1,550.50 mi (2,495.29 km) |
| Ioannina to Tondela | 1,523.75 mi (2,452.24 km) |
| Ioannina to Torre de Moncorvo | 1,469.29 mi (2,364.59 km) |
| Ioannina to Torres Novas | 1,558.19 mi (2,507.66 km) |
| Ioannina to Torres Vedras | 1,601.59 mi (2,577.52 km) |
