| Isabela to Sacile | 4,811.37 mi (7,743.16 km) |
| Isabela to Sala Consilina | 5,018.91 mi (8,077.15 km) |
| Isabela to Salemi | 4,899.95 mi (7,885.71 km) |
| Isabela to Salerno | 4,972.19 mi (8,001.96 km) |
| Isabela to Salo | 4,719.36 mi (7,595.07 km) |
| Isabela to Salsomaggiore Terme | 4,696.90 mi (7,558.93 km) |
| Isabela to Saluzzo | 4,575.78 mi (7,364.00 km) |
| Isabela to Salzano | 4,796.05 mi (7,718.49 km) |
| Isabela to Samarate | 4,634.91 mi (7,459.16 km) |
| Isabela to San Benedetto del Tronto | 4,904.21 mi (7,892.56 km) |
| Isabela to San Biagio di Callalta | 4,807.70 mi (7,737.24 km) |
| Isabela to San Bonifacio | 4,756.74 mi (7,655.24 km) |
| Isabela to San Casciano in Val di Pesa | 4,763.69 mi (7,666.42 km) |
| Isabela to San Cataldo | 4,967.57 mi (7,994.54 km) |
| Isabela to San Cesareo | 4,860.00 mi (7,821.41 km) |
