| Isabela to Savignano sul Rubicone | 4,820.26 mi (7,757.46 km) |
| Isabela to Savona | 4,625.90 mi (7,444.67 km) |
| Isabela to Scafati | 4,959.27 mi (7,981.17 km) |
| Isabela to Scalea | 5,036.29 mi (8,105.13 km) |
| Isabela to Scandiano | 4,732.86 mi (7,616.81 km) |
| Isabela to Scandicci | 4,763.18 mi (7,665.60 km) |
| Isabela to Schio | 4,758.26 mi (7,657.68 km) |
| Isabela to Sciacca | 4,918.92 mi (7,916.24 km) |
| Isabela to Scicli | 5,014.95 mi (8,070.79 km) |
| Isabela to Scordia | 5,016.63 mi (8,073.49 km) |
| Isabela to Scorze | 4,795.40 mi (7,717.46 km) |
| Isabela to Sedico | 4,791.25 mi (7,710.77 km) |
| Isabela to Sedriano | 4,644.34 mi (7,474.34 km) |
| Isabela to Segni | 4,872.30 mi (7,841.21 km) |
| Isabela to Segrate | 4,660.19 mi (7,499.85 km) |
