| Isabela to El Astillero | 4,013.36 mi (6,458.87 km) |
| Isabela to El Ejido | 4,051.26 mi (6,519.87 km) |
| Isabela to El Escorial | 3,985.76 mi (6,414.46 km) |
| Isabela to El Espinar | 3,979.84 mi (6,404.93 km) |
| Isabela to El Molar | 4,014.74 mi (6,461.10 km) |
| Isabela to El Prat de Llobregat | 4,311.08 mi (6,938.01 km) |
| Isabela to El Puerto de Santa Maria | 3,862.79 mi (6,216.56 km) |
| Isabela to El Viso del Alcor | 3,891.86 mi (6,263.34 km) |
| Isabela to Elche | 4,166.14 mi (6,704.75 km) |
| Isabela to Elda | 4,160.61 mi (6,695.85 km) |
| Isabela to Elgoibar | 4,082.88 mi (6,570.77 km) |
| Isabela to Erandio | 4,055.31 mi (6,526.40 km) |
| Isabela to Ermua | 4,078.56 mi (6,563.81 km) |
| Isabela to Esparraguera | 4,299.15 mi (6,918.81 km) |
| Isabela to Espartinas | 3,869.91 mi (6,228.01 km) |
