| Isabela to Shoreham-by-Sea | 4,225.42 mi (6,800.16 km) |
| Isabela to Shotley Bridge | 4,196.98 mi (6,754.38 km) |
| Isabela to Shrewsbury | 4,137.00 mi (6,657.86 km) |
| Isabela to Sidcup | 4,245.82 mi (6,832.99 km) |
| Isabela to Sidmouth | 4,095.47 mi (6,591.02 km) |
| Isabela to Sileby | 4,205.48 mi (6,768.06 km) |
| Isabela to Sittingbourne | 4,272.60 mi (6,876.08 km) |
| Isabela to Skegness | 4,268.88 mi (6,870.09 km) |
| Isabela to Skelmersdale | 4,145.45 mi (6,671.46 km) |
| Isabela to Skipton | 4,180.68 mi (6,728.16 km) |
| Isabela to Sleaford | 4,236.50 mi (6,817.99 km) |
| Isabela to Slough | 4,216.89 mi (6,786.43 km) |
| Isabela to Small Heath | 4,171.84 mi (6,713.92 km) |
| Isabela to Smethwick | 4,167.37 mi (6,706.73 km) |
| Isabela to Snaresbrook | 4,243.22 mi (6,828.81 km) |
