| Isabela to Cloverleaf (Texas) | 1,931.65 mi (3,108.70 km) |
| Isabela to Cloverly (Maryland) | 1,544.16 mi (2,485.09 km) |
| Isabela to Clovis (California) | 3,414.16 mi (5,494.56 km) |
| Isabela to Clovis (New Mexico) | 2,475.22 mi (3,983.49 km) |
| Isabela to Clute (Texas) | 1,929.60 mi (3,105.39 km) |
| Isabela to Coachella (California) | 3,190.65 mi (5,134.86 km) |
| Isabela to Coalinga (California) | 3,444.31 mi (5,543.08 km) |
| Isabela to Coamo (Puerto Rico) | 52.13 mi (83.89 km) |
| Isabela to Coatesville (Pennsylvania) | 1,574.35 mi (2,533.67 km) |
| Isabela to Cockeysville (Maryland) | 1,559.23 mi (2,509.34 km) |
| Isabela to Cocoa (Florida) | 1,105.43 mi (1,779.02 km) |
| Isabela to Cocoa Beach (Florida) | 1,096.51 mi (1,764.67 km) |
| Isabela to Coconut Creek (Florida) | 996.99 mi (1,604.51 km) |
| Isabela to Coeur d'Alene (Idaho) | 3,433.59 mi (5,525.82 km) |
| Isabela to Cohoes (New York) | 1,722.20 mi (2,771.61 km) |
