| Isabela to Delaware (Ohio) | 1,782.13 mi (2,868.07 km) |
| Isabela to Delhi (California) | 3,478.84 mi (5,598.65 km) |
| Isabela to Delray Beach (Florida) | 998.08 mi (1,606.26 km) |
| Isabela to Deltona (Florida) | 1,148.42 mi (1,848.21 km) |
| Isabela to Deming (New Mexico) | 2,695.24 mi (4,337.57 km) |
| Isabela to Denison (Texas) | 2,103.67 mi (3,385.52 km) |
| Isabela to Dent (Ohio) | 1,776.96 mi (2,859.74 km) |
| Isabela to Denton (Texas) | 2,119.52 mi (3,411.04 km) |
| Isabela to Dentsville (South Carolina) | 1,376.40 mi (2,215.11 km) |
| Isabela to Denver (Colorado) | 2,685.91 mi (4,322.55 km) |
| Isabela to Depew (New York) | 1,819.67 mi (2,928.48 km) |
| Isabela to Derby (Connecticut) | 1,617.36 mi (2,602.89 km) |
| Isabela to Derby (Kansas) | 2,248.90 mi (3,619.26 km) |
| Isabela to Des Moines (Iowa) | 2,233.85 mi (3,595.03 km) |
| Isabela to Des Moines (Washington) | 3,675.57 mi (5,915.25 km) |
