| Isabela to Duluth (Minnesota) | 2,417.53 mi (3,890.64 km) |
| Isabela to Dumas (Texas) | 2,440.70 mi (3,927.92 km) |
| Isabela to Dumont (New Jersey) | 1,604.88 mi (2,582.80 km) |
| Isabela to Duncan (Oklahoma) | 2,194.93 mi (3,532.40 km) |
| Isabela to Duncanville (Texas) | 2,093.08 mi (3,368.49 km) |
| Isabela to Dundalk (Maryland) | 1,543.03 mi (2,483.27 km) |
| Isabela to Dunedin (Florida) | 1,196.07 mi (1,924.88 km) |
| Isabela to Dunkirk (New York) | 1,807.19 mi (2,908.39 km) |
| Isabela to Dunmore (Pennsylvania) | 1,662.50 mi (2,675.54 km) |
| Isabela to Dunwoody (Georgia) | 1,507.73 mi (2,426.45 km) |
| Isabela to Durango (Colorado) | 2,782.71 mi (4,478.34 km) |
| Isabela to Durant (Oklahoma) | 2,099.82 mi (3,379.34 km) |
| Isabela to Durham (North Carolina) | 1,408.35 mi (2,266.52 km) |
| Isabela to Dyer (Indiana) | 1,995.77 mi (3,211.88 km) |
| Isabela to Dyersburg (Tennessee) | 1,822.94 mi (2,933.73 km) |
