| Isabela to Eatontown (New Jersey) | 1,562.72 mi (2,514.96 km) |
| Isabela to Eau Claire (Wisconsin) | 2,300.19 mi (3,701.80 km) |
| Isabela to Echelon (New Jersey) | 1,549.82 mi (2,494.20 km) |
| Isabela to Eden (North Carolina) | 1,464.70 mi (2,357.21 km) |
| Isabela to Eden Prairie (Minnesota) | 2,372.07 mi (3,817.48 km) |
| Isabela to Edgewater (Florida) | 1,137.27 mi (1,830.26 km) |
| Isabela to Edgewater (New Jersey) | 1,596.57 mi (2,569.43 km) |
| Isabela to Edgewood (Maryland) | 1,548.13 mi (2,491.47 km) |
| Isabela to Edgewood (Washington) | 3,671.57 mi (5,908.82 km) |
| Isabela to Edina (Minnesota) | 2,370.39 mi (3,814.78 km) |
| Isabela to Edinburg (Texas) | 2,055.24 mi (3,307.59 km) |
| Isabela to Edmond (Oklahoma) | 2,199.72 mi (3,540.11 km) |
| Isabela to Edmonds (Washington) | 3,683.96 mi (5,928.76 km) |
| Isabela to Edwards (Colorado) | 2,768.88 mi (4,456.08 km) |
| Isabela to Edwardsville (Illinois) | 1,964.77 mi (3,161.98 km) |
