| Isabela to Eugene (Oregon) | 3,667.01 mi (5,901.48 km) |
| Isabela to Euless (Texas) | 2,107.15 mi (3,391.13 km) |
| Isabela to Eureka (California) | 3,686.23 mi (5,932.41 km) |
| Isabela to Eureka (Missouri) | 1,980.29 mi (3,186.97 km) |
| Isabela to Eustis (Florida) | 1,169.44 mi (1,882.03 km) |
| Isabela to Evans (Colorado) | 2,695.13 mi (4,337.39 km) |
| Isabela to Evans (Georgia) | 1,397.78 mi (2,249.51 km) |
| Isabela to Evanston (Illinois) | 2,029.93 mi (3,266.86 km) |
| Isabela to Evanston (Wyoming) | 3,021.80 mi (4,863.11 km) |
| Isabela to Evansville (Indiana) | 1,827.56 mi (2,941.18 km) |
| Isabela to Everett (Massachusetts) | 1,668.69 mi (2,685.49 km) |
| Isabela to Everett (Washington) | 3,677.86 mi (5,918.94 km) |
| Isabela to Evergreen Park (Illinois) | 2,013.82 mi (3,240.92 km) |
| Isabela to Ewa Beach (Hawaii) | 5,821.23 mi (9,368.37 km) |
| Isabela to Ewa Gentry (Hawaii) | 5,822.05 mi (9,369.68 km) |
