| Isabela to Largo (Florida) | 1,191.00 mi (1,916.74 km) |
| Isabela to Largo (Maryland) | 1,526.10 mi (2,456.02 km) |
| Isabela to Larkspur (California) | 3,578.06 mi (5,758.34 km) |
| Isabela to Las Cruces (New Mexico) | 2,640.84 mi (4,250.02 km) |
| Isabela to Las Vegas (Nevada) | 3,165.57 mi (5,094.50 km) |
| Isabela to Las Vegas (New Mexico) | 2,608.37 mi (4,197.77 km) |
| Isabela to Latham (New York) | 1,720.72 mi (2,769.24 km) |
| Isabela to Lathrop (California) | 3,511.05 mi (5,650.48 km) |
| Isabela to Lauderdale Lakes (Florida) | 994.10 mi (1,599.84 km) |
| Isabela to Lauderhill (Florida) | 995.04 mi (1,601.37 km) |
| Isabela to Laurel (Florida) | 1,148.63 mi (1,848.55 km) |
| Isabela to Laurel (Maryland) | 1,540.28 mi (2,478.85 km) |
| Isabela to Laurel (Mississippi) | 1,651.97 mi (2,658.59 km) |
| Isabela to Laurel (Virginia) | 1,466.22 mi (2,359.65 km) |
| Isabela to Laurinburg (North Carolina) | 1,358.92 mi (2,186.97 km) |
