| Isabela to Lowell (Indiana) | 1,982.24 mi (3,190.11 km) |
| Isabela to Lowell (Massachusetts) | 1,686.80 mi (2,714.65 km) |
| Isabela to Lower Burrell (Pennsylvania) | 1,701.53 mi (2,738.35 km) |
| Isabela to Lowes Island (Virginia) | 1,548.79 mi (2,492.54 km) |
| Isabela to Lubbock (Texas) | 2,386.15 mi (3,840.14 km) |
| Isabela to Lufkin (Texas) | 1,941.08 mi (3,123.87 km) |
| Isabela to Luling (Louisiana) | 1,663.07 mi (2,676.45 km) |
| Isabela to Lumberton (North Carolina) | 1,336.13 mi (2,150.29 km) |
| Isabela to Lumberton (Texas) | 1,886.97 mi (3,036.78 km) |
| Isabela to Lutz (Florida) | 1,181.98 mi (1,902.21 km) |
| Isabela to Lynbrook (New York) | 1,581.08 mi (2,544.51 km) |
| Isabela to Lynchburg (Virginia) | 1,499.13 mi (2,412.61 km) |
| Isabela to Lynden (Washington) | 3,707.27 mi (5,966.27 km) |
| Isabela to Lyndhurst (Ohio) | 1,804.87 mi (2,904.67 km) |
| Isabela to Lyndon (Kentucky) | 1,764.22 mi (2,839.24 km) |
