| Isabela to Medford (New York) | 1,582.35 mi (2,546.55 km) |
| Isabela to Medford (Oregon) | 3,634.25 mi (5,848.75 km) |
| Isabela to Medina (Ohio) | 1,793.51 mi (2,886.38 km) |
| Isabela to Medulla (Florida) | 1,151.44 mi (1,853.06 km) |
| Isabela to Mehlville (Missouri) | 1,966.08 mi (3,164.10 km) |
| Isabela to Melbourne (Florida) | 1,089.40 mi (1,753.22 km) |
| Isabela to Melissa (Texas) | 2,089.91 mi (3,363.39 km) |
| Isabela to Melrose (Massachusetts) | 1,672.08 mi (2,690.95 km) |
| Isabela to Melrose Park (Illinois) | 2,028.68 mi (3,264.84 km) |
| Isabela to Melville (New York) | 1,585.51 mi (2,551.63 km) |
| Isabela to Melvindale (Michigan) | 1,896.87 mi (3,052.72 km) |
| Isabela to Memphis (Florida) | 1,167.41 mi (1,878.76 km) |
| Isabela to Memphis (Tennessee) | 1,813.48 mi (2,918.51 km) |
| Isabela to Menasha (Wisconsin) | 2,165.42 mi (3,484.91 km) |
| Isabela to Mendota (California) | 3,451.76 mi (5,555.07 km) |
