| Isabela to Saddlebrooke (Arizona) | 2,878.15 mi (4,631.93 km) |
| Isabela to Safety Harbor (Florida) | 1,190.47 mi (1,915.87 km) |
| Isabela to Saginaw (Michigan) | 1,983.81 mi (3,192.63 km) |
| Isabela to Saginaw (Texas) | 2,123.03 mi (3,416.68 km) |
| Isabela to Sahuarita (Arizona) | 2,877.18 mi (4,630.37 km) |
| Isabela to Saks (Alabama) | 1,566.43 mi (2,520.92 km) |
| Isabela to Salem (Massachusetts) | 1,674.71 mi (2,695.19 km) |
| Isabela to Salem (Ohio) | 1,751.26 mi (2,818.38 km) |
| Isabela to Salem (Oregon) | 3,673.34 mi (5,911.67 km) |
| Isabela to Salem (Virginia) | 1,519.00 mi (2,444.60 km) |
| Isabela to Salem Lakes (Wisconsin) | 2,069.90 mi (3,331.19 km) |
| Isabela to Salida (California) | 3,497.83 mi (5,629.21 km) |
| Isabela to Salina (Kansas) | 2,306.98 mi (3,712.73 km) |
| Isabela to Salinas (California) | 3,520.37 mi (5,665.49 km) |
| Isabela to Salisbury (Maryland) | 1,466.82 mi (2,360.62 km) |
