| Isabela to Shelton (Connecticut) | 1,616.72 mi (2,601.85 km) |
| Isabela to Shelton (Washington) | 3,709.32 mi (5,969.57 km) |
| Isabela to Shenandoah (Louisiana) | 1,712.35 mi (2,755.75 km) |
| Isabela to Shepherdsville (Kentucky) | 1,754.61 mi (2,823.77 km) |
| Isabela to Sheridan (Wyoming) | 2,923.39 mi (4,704.74 km) |
| Isabela to Sherman (Texas) | 2,102.17 mi (3,383.11 km) |
| Isabela to Sherrelwood (Colorado) | 2,694.08 mi (4,335.71 km) |
| Isabela to Sherwood (Arkansas) | 1,912.17 mi (3,077.34 km) |
| Isabela to Sherwood (Oregon) | 3,670.41 mi (5,906.95 km) |
| Isabela to Shiloh (Illinois) | 1,951.41 mi (3,140.49 km) |
| Isabela to Shiloh (Ohio) | 1,794.82 mi (2,888.48 km) |
| Isabela to Shiloh (Pennsylvania) | 1,593.82 mi (2,565.00 km) |
| Isabela to Shirley (New York) | 1,579.00 mi (2,541.15 km) |
| Isabela to Shively (Kentucky) | 1,769.48 mi (2,847.71 km) |
| Isabela to Shoreline (Washington) | 3,682.59 mi (5,926.56 km) |
