| Isabela to Spout Springs (North Carolina) | 1,372.44 mi (2,208.73 km) |
| Isabela to Spring (Texas) | 1,949.36 mi (3,137.19 km) |
| Isabela to Spring Creek (Nevada) | 3,244.93 mi (5,222.21 km) |
| Isabela to Spring Hill (Florida) | 1,198.53 mi (1,928.85 km) |
| Isabela to Spring Hill (Tennessee) | 1,700.65 mi (2,736.94 km) |
| Isabela to Spring Lake (North Carolina) | 1,366.28 mi (2,198.81 km) |
| Isabela to Spring Valley (California) | 3,232.06 mi (5,201.49 km) |
| Isabela to Spring Valley (Nevada) | 3,163.92 mi (5,091.84 km) |
| Isabela to Spring Valley (New York) | 1,616.96 mi (2,602.25 km) |
| Isabela to Springboro (Ohio) | 1,781.46 mi (2,866.98 km) |
| Isabela to Springdale (Arkansas) | 2,053.39 mi (3,304.61 km) |
| Isabela to Springdale (New Jersey) | 1,551.26 mi (2,496.51 km) |
| Isabela to Springdale (Ohio) | 1,775.63 mi (2,857.61 km) |
| Isabela to Springfield (Illinois) | 1,994.52 mi (3,209.88 km) |
| Isabela to Springfield (Massachusetts) | 1,663.65 mi (2,677.38 km) |
