| Isabela to St. George (Utah) | 3,084.00 mi (4,963.22 km) |
| Isabela to St. Helens (Oregon) | 3,675.99 mi (5,915.94 km) |
| Isabela to St. James (New York) | 1,588.19 mi (2,555.95 km) |
| Isabela to St. John (Indiana) | 1,991.62 mi (3,205.20 km) |
| Isabela to St. Joseph (Missouri) | 2,212.81 mi (3,561.17 km) |
| Isabela to St. Louis (Missouri) | 1,968.86 mi (3,168.57 km) |
| Isabela to St. Louis Park (Minnesota) | 2,373.20 mi (3,819.30 km) |
| Isabela to St. Marys (Georgia) | 1,243.56 mi (2,001.31 km) |
| Isabela to St. Marys (Pennsylvania) | 1,725.62 mi (2,777.11 km) |
| Isabela to St. Matthews (Kentucky) | 1,765.37 mi (2,841.09 km) |
| Isabela to St. Michael (Minnesota) | 2,396.73 mi (3,857.16 km) |
| Isabela to St. Paul (Minnesota) | 2,363.66 mi (3,803.95 km) |
| Isabela to St. Peter (Minnesota) | 2,367.42 mi (3,809.99 km) |
| Isabela to St. Peters (Missouri) | 1,990.41 mi (3,203.26 km) |
| Isabela to St. Petersburg (Florida) | 1,181.42 mi (1,901.32 km) |
