| Isabela to St. Simons (Georgia) | 1,253.91 mi (2,017.97 km) |
| Isabela to Stafford (Texas) | 1,950.94 mi (3,139.73 km) |
| Isabela to Stallings (North Carolina) | 1,419.47 mi (2,284.42 km) |
| Isabela to Stamford (Connecticut) | 1,609.01 mi (2,589.45 km) |
| Isabela to Stanford (California) | 3,554.71 mi (5,720.75 km) |
| Isabela to Stanton (California) | 3,297.18 mi (5,306.30 km) |
| Isabela to Star (Idaho) | 3,339.76 mi (5,374.83 km) |
| Isabela to Starkville (Mississippi) | 1,697.37 mi (2,731.66 km) |
| Isabela to State College (Pennsylvania) | 1,668.72 mi (2,685.55 km) |
| Isabela to Staten Island (New York) | 1,583.45 mi (2,548.32 km) |
| Isabela to Statesboro (Georgia) | 1,329.09 mi (2,138.96 km) |
| Isabela to Statesville (North Carolina) | 1,463.14 mi (2,354.70 km) |
| Isabela to Staunton (Virginia) | 1,539.80 mi (2,478.07 km) |
| Isabela to Steamboat Springs (Colorado) | 2,799.81 mi (4,505.85 km) |
| Isabela to Steiner Ranch (Texas) | 2,099.10 mi (3,378.18 km) |
