| Iserlohn to Skarzysko-Kamienna | 572.54 mi (921.41 km) |
| Iserlohn to Skawina | 540.68 mi (870.14 km) |
| Iserlohn to Skierniewice | 535.72 mi (862.15 km) |
| Iserlohn to Skoczow | 499.41 mi (803.72 km) |
| Iserlohn to Skwierzyna | 343.52 mi (552.85 km) |
| Iserlohn to Slawno | 427.81 mi (688.49 km) |
| Iserlohn to Slubice | 301.74 mi (485.61 km) |
| Iserlohn to Slupca | 439.63 mi (707.51 km) |
| Iserlohn to Slupsk | 443.85 mi (714.31 km) |
| Iserlohn to Sochaczew | 539.36 mi (868.01 km) |
| Iserlohn to Sokolka | 680.48 mi (1,095.13 km) |
| Iserlohn to Sokolow Podlaski | 624.72 mi (1,005.39 km) |
| Iserlohn to Solec Kujawski | 461.83 mi (743.24 km) |
| Iserlohn to Sopot | 500.41 mi (805.33 km) |
| Iserlohn to Sosnowiec | 505.58 mi (813.65 km) |
