| Iserlohn to Sangeorz-Bai | 811.76 mi (1,306.40 km) |
| Iserlohn to Sannicolau Mare | 693.70 mi (1,116.41 km) |
| Iserlohn to Santana | 716.87 mi (1,153.69 km) |
| Iserlohn to Satu Mare | 724.05 mi (1,165.25 km) |
| Iserlohn to Scobinti | 906.50 mi (1,458.87 km) |
| Iserlohn to Scornicesti | 908.63 mi (1,462.30 km) |
| Iserlohn to Sebes | 814.32 mi (1,310.52 km) |
| Iserlohn to Seini | 741.86 mi (1,193.91 km) |
| Iserlohn to Sfantu-Gheorghe | 908.05 mi (1,461.37 km) |
| Iserlohn to Sibiu | 844.07 mi (1,358.40 km) |
| Iserlohn to Sighetu Marmatiei | 762.13 mi (1,226.53 km) |
| Iserlohn to Sighisoara | 854.53 mi (1,375.23 km) |
| Iserlohn to Simeria | 796.13 mi (1,281.25 km) |
| Iserlohn to Sinaia | 917.44 mi (1,476.48 km) |
| Iserlohn to Slatina | 907.28 mi (1,460.12 km) |
