| Isernia to Seysses | 670.17 mi (1,078.53 km) |
| Isernia to Sin-le-Noble | 805.56 mi (1,296.42 km) |
| Isernia to Six-Fours-les-Plages | 441.99 mi (711.32 km) |
| Isernia to Soissons | 752.48 mi (1,211.00 km) |
| Isernia to Soisy-sous-Montmorency | 771.12 mi (1,241.00 km) |
| Isernia to Sollies-Pont | 432.27 mi (695.67 km) |
| Isernia to Somain | 800.04 mi (1,287.55 km) |
| Isernia to Sorgues | 502.73 mi (809.07 km) |
| Isernia to Sotteville-les-Rouen | 832.40 mi (1,339.61 km) |
| Isernia to Soyaux | 754.43 mi (1,214.14 km) |
| Isernia to Stains | 766.52 mi (1,233.60 km) |
| Isernia to Stiring-Wendel | 632.83 mi (1,018.44 km) |
| Isernia to Strasbourg | 576.54 mi (927.85 km) |
| Isernia to Sucy-en-Brie | 753.98 mi (1,213.41 km) |
| Isernia to Suresnes | 769.18 mi (1,237.87 km) |
