| Isernia to Selvazzano Dentro | 288.73 mi (464.67 km) |
| Isernia to Senago | 375.26 mi (603.92 km) |
| Isernia to Senigallia | 154.77 mi (249.07 km) |
| Isernia to Seravezza | 262.02 mi (421.68 km) |
| Isernia to Seregno | 376.31 mi (605.61 km) |
| Isernia to Seriate | 361.34 mi (581.52 km) |
| Isernia to Sermoneta | 65.04 mi (104.67 km) |
| Isernia to Serramanna | 317.28 mi (510.62 km) |
| Isernia to Serravalle Pistoiese | 234.61 mi (377.57 km) |
| Isernia to Sessa Aurunca | 30.06 mi (48.38 km) |
| Isernia to Sesto Calende | 399.75 mi (643.34 km) |
| Isernia to Sesto Fiorentino | 218.05 mi (350.92 km) |
| Isernia to Sesto San Giovanni | 369.40 mi (594.49 km) |
| Isernia to Sestri Levante | 306.74 mi (493.64 km) |
| Isernia to Sestu | 313.90 mi (505.18 km) |
