| Isernia to Rybnik | 621.32 mi (999.91 km) |
| Isernia to Ryki | 782.32 mi (1,259.02 km) |
| Isernia to Rypin | 828.24 mi (1,332.93 km) |
| Isernia to Rzeszow | 691.21 mi (1,112.40 km) |
| Isernia to Sandomierz | 722.25 mi (1,162.35 km) |
| Isernia to Sanok | 670.25 mi (1,078.66 km) |
| Isernia to Sedziszow Malopolski | 685.49 mi (1,103.18 km) |
| Isernia to Sepolno Krajenskie | 832.60 mi (1,339.94 km) |
| Isernia to Sidlice | 903.08 mi (1,453.36 km) |
| Isernia to Siechnice | 666.33 mi (1,072.36 km) |
| Isernia to Siedlce | 821.28 mi (1,321.72 km) |
| Isernia to Siemianowice Slaskie | 640.83 mi (1,031.32 km) |
| Isernia to Siemiatycze | 849.70 mi (1,367.46 km) |
| Isernia to Sieradz | 722.80 mi (1,163.24 km) |
| Isernia to Sierpc | 819.33 mi (1,318.59 km) |
