| Isernia to Skarzysko-Kamienna | 729.66 mi (1,174.28 km) |
| Isernia to Skawina | 638.22 mi (1,027.12 km) |
| Isernia to Skierniewice | 768.10 mi (1,236.14 km) |
| Isernia to Skoczow | 607.16 mi (977.13 km) |
| Isernia to Skwierzyna | 762.11 mi (1,226.50 km) |
| Isernia to Slawno | 888.35 mi (1,429.66 km) |
| Isernia to Slubice | 742.72 mi (1,195.29 km) |
| Isernia to Slupca | 758.39 mi (1,220.51 km) |
| Isernia to Slupsk | 897.86 mi (1,444.96 km) |
| Isernia to Sochaczew | 786.41 mi (1,265.60 km) |
| Isernia to Sokolka | 920.86 mi (1,481.99 km) |
| Isernia to Sokolow Podlaski | 834.86 mi (1,343.59 km) |
| Isernia to Solec Kujawski | 814.63 mi (1,311.02 km) |
| Isernia to Sopot | 909.46 mi (1,463.63 km) |
| Isernia to Sosnowiec | 643.84 mi (1,036.17 km) |
