| Isernia to Castelo Branco | 1,142.21 mi (1,838.21 km) |
| Isernia to Castro Daire | 1,149.65 mi (1,850.19 km) |
| Isernia to Celorico de Basto | 1,147.88 mi (1,847.34 km) |
| Isernia to Chamusca | 1,200.82 mi (1,932.54 km) |
| Isernia to Chaves | 1,117.57 mi (1,798.56 km) |
| Isernia to Cinfaes | 1,157.67 mi (1,863.09 km) |
| Isernia to Coimbra | 1,184.22 mi (1,905.82 km) |
| Isernia to Condeixa-a-Nova | 1,189.26 mi (1,913.92 km) |
| Isernia to Corroios | 1,249.20 mi (2,010.39 km) |
| Isernia to Coruche | 1,210.27 mi (1,947.74 km) |
| Isernia to Costa de Caparica | 1,252.97 mi (2,016.47 km) |
| Isernia to Covilha | 1,135.24 mi (1,827.00 km) |
| Isernia to Eiras | 1,183.51 mi (1,904.67 km) |
| Isernia to Elvas | 1,140.90 mi (1,836.11 km) |
| Isernia to Entroncamento | 1,198.03 mi (1,928.04 km) |
