| Isernia to Ericeira | 1,256.21 mi (2,021.67 km) |
| Isernia to Ermezinde | 1,177.82 mi (1,895.51 km) |
| Isernia to Esmoriz | 1,184.70 mi (1,906.59 km) |
| Isernia to Espinho | 1,184.73 mi (1,906.64 km) |
| Isernia to Esposende | 1,186.59 mi (1,909.64 km) |
| Isernia to Estarreja | 1,184.07 mi (1,905.57 km) |
| Isernia to Estoril | 1,260.19 mi (2,028.08 km) |
| Isernia to Estremoz | 1,163.60 mi (1,872.63 km) |
| Isernia to Evora | 1,185.60 mi (1,908.04 km) |
| Isernia to Fafe | 1,155.79 mi (1,860.06 km) |
| Isernia to Falagueira | 1,250.22 mi (2,012.03 km) |
| Isernia to Famalicao | 1,174.06 mi (1,889.47 km) |
| Isernia to Fanzeres | 1,177.50 mi (1,895.00 km) |
| Isernia to Faro | 1,223.27 mi (1,968.67 km) |
| Isernia to Fatima | 1,205.54 mi (1,940.13 km) |
