| Isernia to Marco de Canavezes | 1,157.63 mi (1,863.03 km) |
| Isernia to Marinha Grande | 1,217.31 mi (1,959.07 km) |
| Isernia to Massama | 1,252.77 mi (2,016.14 km) |
| Isernia to Matosinhos | 1,185.88 mi (1,908.49 km) |
| Isernia to Mealhada | 1,182.87 mi (1,903.64 km) |
| Isernia to Melgaco | 1,155.36 mi (1,859.37 km) |
| Isernia to Melres | 1,171.75 mi (1,885.75 km) |
| Isernia to Mira | 1,196.79 mi (1,926.04 km) |
| Isernia to Miranda do Corvo | 1,180.90 mi (1,900.48 km) |
| Isernia to Mirandela | 1,104.93 mi (1,778.21 km) |
| Isernia to Mogadouro | 1,082.47 mi (1,742.07 km) |
| Isernia to Moimenta da Beira | 1,132.28 mi (1,822.23 km) |
| Isernia to Moita | 1,239.84 mi (1,995.32 km) |
| Isernia to Moncao | 1,166.54 mi (1,877.37 km) |
| Isernia to Montalegre | 1,133.30 mi (1,823.87 km) |
