| Isernia to Ramnicu Sarat | 692.61 mi (1,114.65 km) |
| Isernia to Ramnicu Valcea | 563.24 mi (906.45 km) |
| Isernia to Rasnov | 624.73 mi (1,005.41 km) |
| Isernia to Reghin | 629.03 mi (1,012.32 km) |
| Isernia to Resita | 460.66 mi (741.36 km) |
| Isernia to Roman | 726.53 mi (1,169.23 km) |
| Isernia to Rosiori de Vede | 571.11 mi (919.12 km) |
| Isernia to Rovinari | 503.46 mi (810.24 km) |
| Isernia to Roznov | 705.92 mi (1,136.07 km) |
| Isernia to Sabaoani | 725.78 mi (1,168.03 km) |
| Isernia to Sacele | 636.60 mi (1,024.51 km) |
| Isernia to Sacueni | 554.12 mi (891.77 km) |
| Isernia to Salcea | 726.93 mi (1,169.88 km) |
| Isernia to Salonta | 513.06 mi (825.69 km) |
| Isernia to Sangeorgiu de Mures | 611.23 mi (983.68 km) |
