| Islington to Southern Pines (North Carolina) | 3,933.46 mi (6,330.30 km) |
| Islington to Southfield (Michigan) | 3,752.19 mi (6,038.56 km) |
| Islington to Southgate (Michigan) | 3,762.27 mi (6,054.80 km) |
| Islington to Southlake (Texas) | 4,752.24 mi (7,647.99 km) |
| Islington to Spanaway (Washington) | 4,814.40 mi (7,748.02 km) |
| Islington to Spanish Fork (Utah) | 4,887.50 mi (7,865.67 km) |
| Islington to Spanish Lake (Missouri) | 4,192.65 mi (6,747.41 km) |
| Islington to Spanish Springs (Nevada) | 5,162.81 mi (8,308.73 km) |
| Islington to Sparks (Nevada) | 5,168.96 mi (8,318.64 km) |
| Islington to Spartanburg (South Carolina) | 4,048.69 mi (6,515.74 km) |
| Islington to Spearfish (South Dakota) | 4,398.85 mi (7,079.26 km) |
| Islington to Speedway (Indiana) | 3,991.53 mi (6,423.74 km) |
| Islington to Spencer (Iowa) | 4,165.76 mi (6,704.15 km) |
| Islington to Spokane (Washington) | 4,646.98 mi (7,478.60 km) |
| Islington to Spokane Valley (Washington) | 4,641.70 mi (7,470.09 km) |
