| Ispica to Cividale del Friuli | 648.16 mi (1,043.11 km) |
| Ispica to Civita Castellana | 403.29 mi (649.03 km) |
| Ispica to Civitanova Marche | 454.46 mi (731.38 km) |
| Ispica to Civitavecchia | 402.80 mi (648.24 km) |
| Ispica to Civitella in Val di Chiana | 488.12 mi (785.56 km) |
| Ispica to Clusone | 678.82 mi (1,092.46 km) |
| Ispica to Coccaglio | 658.10 mi (1,059.10 km) |
| Ispica to Codigoro | 574.83 mi (925.10 km) |
| Ispica to Codogno | 638.73 mi (1,027.94 km) |
| Ispica to Codroipo | 641.94 mi (1,033.10 km) |
| Ispica to Cogoleto | 619.12 mi (996.38 km) |
| Ispica to Colle di Val d'Elsa | 498.50 mi (802.26 km) |
| Ispica to Colle Salvetti | 525.32 mi (845.42 km) |
| Ispica to Collecchio | 602.27 mi (969.25 km) |
| Ispica to Colleferro | 356.52 mi (573.76 km) |
