| Ispica to Collegno | 688.33 mi (1,107.77 km) |
| Ispica to Cologno al Serio | 665.06 mi (1,070.32 km) |
| Ispica to Cologno Monzese | 670.86 mi (1,079.65 km) |
| Ispica to Colorno | 610.32 mi (982.21 km) |
| Ispica to Comacchio | 565.08 mi (909.41 km) |
| Ispica to Comiso | 20.19 mi (32.49 km) |
| Ispica to Como | 692.41 mi (1,114.33 km) |
| Ispica to Concordia Sagittaria | 629.69 mi (1,013.39 km) |
| Ispica to Concorezzo | 673.32 mi (1,083.60 km) |
| Ispica to Conegliano | 643.22 mi (1,035.16 km) |
| Ispica to Conselice | 557.87 mi (897.81 km) |
| Ispica to Conselve | 604.76 mi (973.26 km) |
| Ispica to Conversano | 312.64 mi (503.15 km) |
| Ispica to Copertino | 294.77 mi (474.39 km) |
| Ispica to Copparo | 583.15 mi (938.48 km) |
