| Ispica to Sala Consilina | 252.73 mi (406.73 km) |
| Ispica to Salemi | 135.71 mi (218.41 km) |
| Ispica to Salerno | 269.38 mi (433.53 km) |
| Ispica to Salo | 649.84 mi (1,045.82 km) |
| Ispica to Salsomaggiore Terme | 611.39 mi (983.94 km) |
| Ispica to Saluzzo | 666.93 mi (1,073.32 km) |
| Ispica to Salzano | 621.55 mi (1,000.29 km) |
| Ispica to Samarate | 687.69 mi (1,106.73 km) |
| Ispica to San Benedetto del Tronto | 429.47 mi (691.16 km) |
| Ispica to San Biagio di Callalta | 628.84 mi (1,012.02 km) |
| Ispica to San Bonifacio | 624.25 mi (1,004.64 km) |
| Ispica to San Casciano in Val di Pesa | 513.61 mi (826.58 km) |
| Ispica to San Cataldo | 69.92 mi (112.53 km) |
| Ispica to San Cesareo | 365.42 mi (588.08 km) |
| Ispica to San Dona di Piave | 623.10 mi (1,002.78 km) |
