| Ispica to Eemnes | 1,167.21 mi (1,878.45 km) |
| Ispica to Eerbeek | 1,142.86 mi (1,839.26 km) |
| Ispica to Eersel | 1,111.04 mi (1,788.04 km) |
| Ispica to Eijsden | 1,068.19 mi (1,719.09 km) |
| Ispica to Eindhoven | 1,112.67 mi (1,790.67 km) |
| Ispica to Elburg | 1,168.24 mi (1,880.09 km) |
| Ispica to Emmeloord | 1,186.22 mi (1,909.03 km) |
| Ispica to Emmen | 1,171.30 mi (1,885.02 km) |
| Ispica to Enkhuizen | 1,193.93 mi (1,921.44 km) |
| Ispica to Enschede | 1,135.22 mi (1,826.96 km) |
| Ispica to Epe | 1,159.58 mi (1,866.16 km) |
| Ispica to Ermelo | 1,163.25 mi (1,872.08 km) |
| Ispica to Etten-Leur | 1,138.55 mi (1,832.33 km) |
| Ispica to Franeker | 1,220.69 mi (1,964.51 km) |
| Ispica to Geertruidenberg | 1,141.74 mi (1,837.46 km) |
