| Ispica to Schijndel | 1,124.86 mi (1,810.29 km) |
| Ispica to Schinnen | 1,075.05 mi (1,730.13 km) |
| Ispica to Schoonhoven | 1,157.00 mi (1,862.01 km) |
| Ispica to Simpelveld | 1,065.89 mi (1,715.38 km) |
| Ispica to Sint Anthonis | 1,116.57 mi (1,796.95 km) |
| Ispica to Sint Willebrord | 1,138.48 mi (1,832.20 km) |
| Ispica to Sint-Michielsgestel | 1,127.99 mi (1,815.32 km) |
| Ispica to Sint-Oedenrode | 1,121.07 mi (1,804.18 km) |
| Ispica to Sittard | 1,078.45 mi (1,735.59 km) |
| Ispica to Sliedrecht | 1,150.70 mi (1,851.87 km) |
| Ispica to Slochteren | 1,200.57 mi (1,932.14 km) |
| Ispica to Sluis | 1,151.92 mi (1,853.84 km) |
| Ispica to Sneek | 1,207.98 mi (1,944.06 km) |
| Ispica to Soest | 1,162.15 mi (1,870.30 km) |
| Ispica to Someren | 1,104.91 mi (1,778.18 km) |
