| Ispica to Skarzysko-Kamienna | 1,033.70 mi (1,663.58 km) |
| Ispica to Skawina | 944.54 mi (1,520.09 km) |
| Ispica to Skierniewice | 1,079.92 mi (1,737.96 km) |
| Ispica to Skoczow | 920.09 mi (1,480.74 km) |
| Ispica to Skwierzyna | 1,093.22 mi (1,759.36 km) |
| Ispica to Slawno | 1,217.25 mi (1,958.97 km) |
| Ispica to Slubice | 1,075.68 mi (1,731.13 km) |
| Ispica to Slupca | 1,081.77 mi (1,740.94 km) |
| Ispica to Slupsk | 1,225.92 mi (1,972.93 km) |
| Ispica to Sochaczew | 1,098.61 mi (1,768.03 km) |
| Ispica to Sokolka | 1,220.23 mi (1,963.77 km) |
| Ispica to Sokolow Podlaski | 1,136.56 mi (1,829.12 km) |
| Ispica to Solec Kujawski | 1,137.64 mi (1,830.86 km) |
| Ispica to Sopot | 1,233.02 mi (1,984.36 km) |
| Ispica to Sosnowiec | 956.15 mi (1,538.77 km) |
