| Ispica to Srem | 1,062.51 mi (1,709.94 km) |
| Ispica to Sroda Slaska | 996.10 mi (1,603.06 km) |
| Ispica to Sroda Wielkopolska | 1,073.78 mi (1,728.08 km) |
| Ispica to Stalowa Wola | 1,015.99 mi (1,635.08 km) |
| Ispica to Starachowice | 1,031.49 mi (1,660.03 km) |
| Ispica to Stargard Szczecinski | 1,143.52 mi (1,840.31 km) |
| Ispica to Starogard Gdanski | 1,199.88 mi (1,931.02 km) |
| Ispica to Stary Sacz | 928.37 mi (1,494.06 km) |
| Ispica to Staszow | 1,001.44 mi (1,611.67 km) |
| Ispica to Strzegom | 982.18 mi (1,580.66 km) |
| Ispica to Strzelce Krajenskie | 1,112.29 mi (1,790.06 km) |
| Ispica to Strzelce Opolskie | 962.44 mi (1,548.90 km) |
| Ispica to Strzelin | 973.21 mi (1,566.23 km) |
| Ispica to Strzyzow | 967.95 mi (1,557.77 km) |
| Ispica to Sucha Beskidzka | 925.33 mi (1,489.17 km) |
