| Ispica to El Ejido | 978.99 mi (1,575.53 km) |
| Ispica to El Escorial | 1,056.87 mi (1,700.87 km) |
| Ispica to El Espinar | 1,064.58 mi (1,713.28 km) |
| Ispica to El Molar | 1,030.28 mi (1,658.07 km) |
| Ispica to El Prat de Llobregat | 754.29 mi (1,213.91 km) |
| Ispica to El Puerto de Santa Maria | 1,167.62 mi (1,879.10 km) |
| Ispica to El Viso del Alcor | 1,134.89 mi (1,826.42 km) |
| Ispica to Elche | 859.82 mi (1,383.75 km) |
| Ispica to Elda | 865.78 mi (1,393.34 km) |
| Ispica to Elgoibar | 1,015.94 mi (1,635.00 km) |
| Ispica to Erandio | 1,044.39 mi (1,680.79 km) |
| Ispica to Ermua | 1,019.29 mi (1,640.38 km) |
| Ispica to Esparraguera | 770.46 mi (1,239.93 km) |
| Ispica to Espartinas | 1,156.79 mi (1,861.67 km) |
| Ispica to Esplugas de Llobregat | 756.01 mi (1,216.68 km) |
