| Ispica to Enumclaw (Washington) | 6,051.64 mi (9,739.17 km) |
| Ispica to Ephrata (Pennsylvania) | 4,697.53 mi (7,559.95 km) |
| Ispica to Erie (Colorado) | 5,904.57 mi (9,502.48 km) |
| Ispica to Erie (Pennsylvania) | 4,802.56 mi (7,728.97 km) |
| Ispica to Erlanger (Kentucky) | 5,118.20 mi (8,236.94 km) |
| Ispica to Escanaba (Michigan) | 4,958.99 mi (7,980.72 km) |
| Ispica to Escondido (California) | 6,699.45 mi (10,781.73 km) |
| Ispica to Española (New Mexico) | 6,144.75 mi (9,889.02 km) |
| Ispica to Essex (Maryland) | 4,740.41 mi (7,628.96 km) |
| Ispica to Essex Junction (Vermont) | 4,417.33 mi (7,109.01 km) |
| Ispica to Estelle (Louisiana) | 5,749.51 mi (9,252.95 km) |
| Ispica to Estero (Florida) | 5,490.30 mi (8,835.79 km) |
| Ispica to Euclid (Ohio) | 4,884.91 mi (7,861.51 km) |
| Ispica to Eufaula (Alabama) | 5,429.89 mi (8,738.57 km) |
| Ispica to Eugene (Oregon) | 6,263.82 mi (10,080.65 km) |
