| Issoudun to Setubal | 800.98 mi (1,289.05 km) |
| Issoudun to Sever do Vouga | 670.53 mi (1,079.11 km) |
| Issoudun to Silves | 859.32 mi (1,382.94 km) |
| Issoudun to Sines | 830.59 mi (1,336.71 km) |
| Issoudun to Sintra | 804.13 mi (1,294.12 km) |
| Issoudun to Sobrado de Paiva | 652.62 mi (1,050.30 km) |
| Issoudun to Sobral de Monte Agraco | 784.40 mi (1,262.36 km) |
| Issoudun to Soure | 713.56 mi (1,148.36 km) |
| Issoudun to Tabua | 675.92 mi (1,087.79 km) |
| Issoudun to Tavira | 839.06 mi (1,350.33 km) |
| Issoudun to Tomar | 728.20 mi (1,171.92 km) |
| Issoudun to Tondela | 670.25 mi (1,078.67 km) |
| Issoudun to Torre de Moncorvo | 601.76 mi (968.43 km) |
| Issoudun to Torres Novas | 739.19 mi (1,189.62 km) |
| Issoudun to Torres Vedras | 785.20 mi (1,263.67 km) |
