| Issoudun to Sangeorz-Bai | 1,062.47 mi (1,709.88 km) |
| Issoudun to Sannicolau Mare | 885.46 mi (1,425.01 km) |
| Issoudun to Santana | 923.74 mi (1,486.61 km) |
| Issoudun to Satu Mare | 976.61 mi (1,571.70 km) |
| Issoudun to Scobinti | 1,166.92 mi (1,877.98 km) |
| Issoudun to Scornicesti | 1,095.78 mi (1,763.48 km) |
| Issoudun to Sebes | 1,026.08 mi (1,651.32 km) |
| Issoudun to Seini | 995.14 mi (1,601.52 km) |
| Issoudun to Sfantu-Gheorghe | 1,131.73 mi (1,821.35 km) |
| Issoudun to Sibiu | 1,055.86 mi (1,699.24 km) |
| Issoudun to Sighetu Marmatiei | 1,022.22 mi (1,645.10 km) |
| Issoudun to Sighisoara | 1,079.99 mi (1,738.08 km) |
| Issoudun to Simeria | 1,001.28 mi (1,611.40 km) |
| Issoudun to Sinaia | 1,128.75 mi (1,816.55 km) |
| Issoudun to Slatina | 1,089.83 mi (1,753.90 km) |
