| Issum to Sanary-sur-Mer | 582.47 mi (937.39 km) |
| Issum to Sannois | 255.49 mi (411.18 km) |
| Issum to Saran | 320.16 mi (515.25 km) |
| Issum to Sarcelles | 250.45 mi (403.06 km) |
| Issum to Sarlat-la-Caneda | 517.86 mi (833.42 km) |
| Issum to Sarrebourg | 195.75 mi (315.03 km) |
| Issum to Sarreguemines | 170.22 mi (273.95 km) |
| Issum to Sartrouville | 260.19 mi (418.74 km) |
| Issum to Sarzeau | 496.20 mi (798.55 km) |
| Issum to Sassenage | 439.01 mi (706.51 km) |
| Issum to Saumur | 415.43 mi (668.58 km) |
| Issum to Savenay | 473.35 mi (761.78 km) |
| Issum to Saverne | 197.70 mi (318.17 km) |
| Issum to Savigny-le-Temple | 265.81 mi (427.78 km) |
| Issum to Savigny-sur-Orge | 267.65 mi (430.73 km) |
