| Issum to Seysses | 604.22 mi (972.40 km) |
| Issum to Sin-le-Noble | 165.40 mi (266.18 km) |
| Issum to Six-Fours-les-Plages | 583.69 mi (939.36 km) |
| Issum to Soissons | 201.97 mi (325.05 km) |
| Issum to Soisy-sous-Montmorency | 253.39 mi (407.80 km) |
| Issum to Sollies-Pont | 577.13 mi (928.80 km) |
| Issum to Somain | 159.31 mi (256.38 km) |
| Issum to Sorgues | 525.24 mi (845.30 km) |
| Issum to Sotteville-les-Rouen | 276.77 mi (445.42 km) |
| Issum to Soyaux | 496.65 mi (799.29 km) |
| Issum to Stains | 252.65 mi (406.60 km) |
| Issum to Stiring-Wendel | 163.13 mi (262.53 km) |
| Issum to Strasbourg | 212.46 mi (341.92 km) |
| Issum to Sucy-en-Brie | 257.67 mi (414.67 km) |
| Issum to Suresnes | 261.76 mi (421.27 km) |
