| Issum to Lendinara | 505.11 mi (812.89 km) |
| Issum to Leno | 460.13 mi (740.51 km) |
| Issum to Lentate sul Seveso | 423.19 mi (681.06 km) |
| Issum to Lentini | 1,070.32 mi (1,722.51 km) |
| Issum to Leonforte | 1,035.75 mi (1,666.88 km) |
| Issum to Lequile | 956.53 mi (1,539.38 km) |
| Issum to Lerici | 540.25 mi (869.44 km) |
| Issum to Leverano | 956.12 mi (1,538.73 km) |
| Issum to Licata | 1,062.77 mi (1,710.37 km) |
| Issum to Limbiate | 428.70 mi (689.92 km) |
| Issum to Lipari | 993.03 mi (1,598.12 km) |
| Issum to Lissone | 429.01 mi (690.43 km) |
| Issum to Livorno | 580.61 mi (934.40 km) |
| Issum to Lizzanello | 958.68 mi (1,542.85 km) |
| Issum to Lizzano | 932.39 mi (1,500.53 km) |
