| Issum to Selvazzano Dentro | 490.80 mi (789.87 km) |
| Issum to Senago | 429.66 mi (691.48 km) |
| Issum to Senigallia | 625.86 mi (1,007.22 km) |
| Issum to Seravezza | 549.92 mi (885.00 km) |
| Issum to Seregno | 426.12 mi (685.78 km) |
| Issum to Seriate | 431.46 mi (694.36 km) |
| Issum to Sermoneta | 756.56 mi (1,217.56 km) |
| Issum to Serramanna | 845.71 mi (1,361.04 km) |
| Issum to Serravalle Pistoiese | 565.94 mi (910.79 km) |
| Issum to Sessa Aurunca | 795.95 mi (1,280.95 km) |
| Issum to Sesto Calende | 413.57 mi (665.58 km) |
| Issum to Sesto Fiorentino | 576.59 mi (927.93 km) |
| Issum to Sesto San Giovanni | 434.31 mi (698.96 km) |
| Issum to Sestri Levante | 520.39 mi (837.49 km) |
| Issum to Sestu | 855.36 mi (1,376.56 km) |
