| Issum to Marco de Canavezes | 993.88 mi (1,599.50 km) |
| Issum to Marinha Grande | 1,097.26 mi (1,765.88 km) |
| Issum to Massama | 1,163.41 mi (1,872.32 km) |
| Issum to Matosinhos | 1,012.07 mi (1,628.77 km) |
| Issum to Mealhada | 1,046.97 mi (1,684.94 km) |
| Issum to Melgaco | 948.62 mi (1,526.66 km) |
| Issum to Melres | 1,008.34 mi (1,622.77 km) |
| Issum to Mira | 1,053.41 mi (1,695.30 km) |
| Issum to Miranda do Corvo | 1,058.83 mi (1,704.03 km) |
| Issum to Mirandela | 946.23 mi (1,522.80 km) |
| Issum to Mogadouro | 939.86 mi (1,512.56 km) |
| Issum to Moimenta da Beira | 987.58 mi (1,589.35 km) |
| Issum to Moita | 1,160.38 mi (1,867.44 km) |
| Issum to Moncao | 958.14 mi (1,541.98 km) |
| Issum to Montalegre | 947.99 mi (1,525.65 km) |
