| Issum to Santiago do Cacem | 1,188.01 mi (1,911.92 km) |
| Issum to Santo Andre | 1,187.59 mi (1,911.24 km) |
| Issum to Santo Tirso | 996.34 mi (1,603.46 km) |
| Issum to Sao Bras de Alportel | 1,215.19 mi (1,955.66 km) |
| Issum to Sao Felix da Marinha | 1,017.45 mi (1,637.43 km) |
| Issum to Sao Joao da Madeira | 1,020.36 mi (1,642.11 km) |
| Issum to Sao Joao de Ver | 1,019.35 mi (1,640.49 km) |
| Issum to Sao Mamede de Infesta | 1,007.85 mi (1,621.98 km) |
| Issum to Sao Pedro do Sul | 1,014.62 mi (1,632.88 km) |
| Issum to Satao | 1,004.89 mi (1,617.22 km) |
| Issum to Seia | 1,021.12 mi (1,643.33 km) |
| Issum to Senhora da Hora | 1,010.29 mi (1,625.91 km) |
| Issum to Serpa | 1,160.10 mi (1,867.00 km) |
| Issum to Serta | 1,068.21 mi (1,719.12 km) |
| Issum to Sesimbra | 1,175.67 mi (1,892.06 km) |
